### Can anybody help me to understand

11/25/2014 7:54:57 PM
Hello

can anybody explain to me this Q ?
the incidence of cystic fibrosis among a populaten of europeans is 1/2500. which is predicted incidence of carriers of a cystic fibrosis mutation in this population

i dont understand how and why ??

11/25/2014 8:56:13 PM
p square+2pq+ q square = 1
q= 1/50 (square root of 2500, since q square is 2500.
2pq is equal 1/50
Therefore pq is 1/25 (since pq is carrier).

Hope you know this much math.

11/25/2014 9:13:36 PM
KuRa18153589 wrote:
p square+2pq+ q square = 1
q= 1/50 (square root of 2500, since q square is 2500.
2pq is equal 1/50
Therefore pq is 1/25 (since pq is carrier).

Hope you know this much math.

thank you so much this is helpful
my problem is in math
but r we assuming p=1 since 2pq = 1/25?

11/25/2014 9:45:25 PM
dr.hno wrote:
Hello

can anybody explain to me this Q ?
the incidence of cystic fibrosis among a populaten of europeans is 1/2500. which is predicted incidence of carriers of a cystic fibrosis mutation in this population

i dont understand how and why ??

I think it is :
(p+q)2 =1 thus p+ 1/25=1 thus p=1-1/25=24/25 =1
p=1 ,q=1/25 thus pq=1/25 11/25/2014 10:00:52 PM
azkh39579794 wrote:
dr.hno wrote:
Hello

can anybody explain to me this Q ?
the incidence of cystic fibrosis among a populaten of europeans is 1/2500. which is predicted incidence of carriers of a cystic fibrosis mutation in this population

i dont understand how and why ??

I think it is :
(p+q)2 =1 thus p+ 1/25=1 thus p=1-1/25=24/25 =1
p=1 ,q=1/25 thus pq=1/25 Ooo thank u so much , I got it now pages: 1

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