Need an explaination!

8/4/2013 4:30:15 PM
Hi,

can anyone explain me how hypothyroidism leads to hypogonadotropic hypogonadism?

Thanks in advance!


8/4/2013 6:55:10 PM
Hey,
With primary Hypothyroidism, there is a subsequent increase in TSH/TRH...this elevation causes dopamine inhibition which will then stimulate prolactin release causing decreased levels of GnRH.
Also, prolactin is stimulated by TRH and serotonin!


8/4/2013 10:26:08 PM
reinaliz wrote:
Hey,
With primary Hypothyroidism, there is a subsequent increase in TSH/TRH...this elevation causes dopamine inhibition which will then stimulate prolactin release causing decreased levels of GnRH.
Also, prolactin is stimulated by TRH and serotonin!


thanks


pages: 1

 | 
We use cookies to learn how you use our website and to ensure that you have the best possible experience.
By continuing to use our website, you are accepting the use of cookies. Learn More
   I Accept